Gene information
Official symbol KCNMA1
Official full name potassium calcium-activated channel subfamily M alpha 1
Gene type protein-coding gene
Chromosome10q22.3
Alias symbolKCa1.1; mSLO1
Previous symbolSLO
Gene familyPotassium calcium-activated channels
Resources
Entrez Gene 3778
HGNC HGNC:6284
Ensembl ENSG00000156113
Vega OTTHUMG00000018543
UCSC uc001jxm.4
GO terms: 63 records
GO Description Category LogP Number of genes Detail
GO:0001666 response to hypoxia GO Biological Processes -40.6131384 77 More
GO:0003012 muscle system process GO Biological Processes -27.3938503 63 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003014 renal system process GO Biological Processes -10.4348518 24 More
GO:0003018 vascular process in circulatory system GO Biological Processes -47.1670528 52 More
GO:0005249 voltage-gated potassium channel activity GO Molecular Functions -1.61932628 4 More
GO:0005261 cation channel activity GO Molecular Functions -1.68739377 23 More
GO:0005267 potassium channel activity GO Molecular Functions -1.81540720 5 More
GO:0005901 caveola GO Cellular Components -18.8033423 19 More
GO:0006813 potassium ion transport GO Biological Processes -2.38043550 7 More
GO:0006884 cell volume homeostasis GO Biological Processes -2.23601792 3 More
GO:0006937 regulation of muscle contraction GO Biological Processes -20.8046481 43 More
GO:0006939 smooth muscle contraction GO Biological Processes -6.47455620 13 More
GO:0006940 regulation of smooth muscle contraction GO Biological Processes -12.9613663 21 More
GO:0006970 response to osmotic stress GO Biological Processes -4.47323224 7 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008076 voltage-gated potassium channel complex GO Cellular Components -1.85589410 4 More
GO:0008361 regulation of cell size GO Biological Processes -4.6524989 21 More
GO:0010035 response to inorganic substance GO Biological Processes -29.1720710 89 More
GO:0010038 response to metal ion GO Biological Processes -20.5090881 61 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0015079 potassium ion transmembrane transporter activity GO Molecular Functions -1.41249432 5 More
GO:0016324 apical plasma membrane GO Cellular Components -4.50542891 15 More
GO:0019725 cellular homeostasis GO Biological Processes -21.1508273 85 More
GO:0030001 metal ion transport GO Biological Processes -7.54203733 26 More
GO:0032535 regulation of cellular component size GO Biological Processes -4.60941253 33 More
GO:0034702 ion channel complex GO Cellular Components -2.54472403 10 More
GO:0034703 cation channel complex GO Cellular Components -2.87762227 9 More
GO:0034705 potassium channel complex GO Cellular Components -2.39849900 5 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0035150 regulation of tube size GO Biological Processes -44.5138102 41 More
GO:0035296 regulation of tube diameter GO Biological Processes -44.6572858 41 More
GO:0036293 response to decreased oxygen levels GO Biological Processes -40.9544531 79 More
GO:0042311 vasodilation GO Biological Processes -18.7593927 16 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0044853 plasma membrane raft GO Cellular Components -18.4542052 33 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0045177 apical part of cell GO Cellular Components -8.17813885 46 More
GO:0045211 postsynaptic membrane GO Cellular Components -5.83105498 30 More
GO:0045932 negative regulation of muscle contraction GO Biological Processes -6.35549828 9 More
GO:0045986 negative regulation of smooth muscle contraction GO Biological Processes -5.72938190 7 More
GO:0046873 metal ion transmembrane transporter activity GO Molecular Functions -1.47457965 10 More
GO:0050801 ion homeostasis GO Biological Processes -12.0812968 60 More
GO:0051592 response to calcium ion GO Biological Processes -7.43492702 23 More
GO:0055067 monovalent inorganic cation homeostasis GO Biological Processes -2.09308401 6 More
GO:0055082 cellular chemical homeostasis GO Biological Processes -17.6289728 71 More
GO:0070482 response to oxygen levels GO Biological Processes -40.7566635 82 More
GO:0071805 potassium ion transmembrane transport GO Biological Processes -1.38276528 5 More
GO:0090066 regulation of anatomical structure size GO Biological Processes -32.7608623 52 More
GO:0090257 regulation of muscle system process GO Biological Processes -33.9441291 67 More
GO:0097746 blood vessel diameter maintenance GO Biological Processes -44.6572858 41 More
GO:0098655 cation transmembrane transport GO Biological Processes -3.98966777 20 More
GO:0098660 inorganic ion transmembrane transport GO Biological Processes -4.47276690 21 More
GO:0098662 inorganic cation transmembrane transport GO Biological Processes -4.65654157 20 More
GO:0098794 postsynapse GO Cellular Components -5.82876983 23 More
GO:0098797 plasma membrane protein complex GO Cellular Components -14.6387951 39 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:1902495 transmembrane transporter complex GO Cellular Components -2.24412383 11 More
KEGG pathways: 3 records
KEGG Description Category LogP Number of genes Detail
hsa04022 cGMP-PKG signaling pathway KEGG Pathway -9.74555098 16 More
hsa04924 Renin secretion KEGG Pathway -9.25913478 11 More
hsa04970 Salivary secretion KEGG Pathway -2.31635881 5 More
Drug-Gene interaction
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Related drugs: 8 records
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
NM_001161352.2:c.[2027+37C>T;687C>T] genomics myocardial infarction[diagnosis] myocardial infarction Tomas M et al. J Hypertens. 2008
NM_001161352.2:c.687C>T genomics myocardial infarction[diagnosis] myocardial infarction Tomas M et al. J Hypertens. 2008
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